Hello and thank you for your interest in our publication:

A Flexible Quadruple-Stranded Helicate Demonstrates a Strong Binding Preference for Three-Way Junctions by Induced-Fit 

In this repository you will find:

Experimental data including:
 - Original, unedited gel images shown in this work in TIF format.
 - Original, unedited spectroscopic (UV-VIS, CD, LD, Fluorescence) data in csv format.
 - Original, unedited NMR data.
 - Original, unedited mass spec characterisation data in PDF format
 - Original, unedited MST reports generated by MO.Affinity Analaysis Software
Simulation data including:
 - All coordinate files for the compounds simulated
 - All simulations in .xtc format with corresponding .pdb or .gro starting frames

----------------------------------------------------------------------------------------------------------------------
A Flexible Quadruple-Stranded Helicate Demonstrates a Strong Binding Preference for Three-Way Junctions by Induced-Fit 
Hugo D. Williams, Samuel J. Dettmer, Sumit Bajpai, Richard Napier, Michael J. Hannon*

University of Birmingham, July 2025