Research data supporting the publication "Neurological and Respiratory Outcomes of the HIPTox Controlled Double-Blind Air Pollution Exposure Trial": processed and raw data

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indexcodes.txt

data http://eprints.org/relation/isVersionOf http://edata.bham.ac.uk/id/document/7791 http://eprints.org/relation/isVolatileVersionOf http://edata.bham.ac.uk/id/document/7791 http://eprints.org/relation/isIndexCodesVersionOf http://edata.bham.ac.uk/id/document/7791 archive 350 disk0/00/00/14/67 2026-04-13 16:50:00 2026-04-13 16:50:00 2026-04-13 16:50:00 data_collection show Faherty Thomas t.b.s.faherty@bham.ac.uk 0000-0003-4064-9034 Badri Huda huda.badri@manchester.ac.uk 0000-0002-6134-4347 Hu Dawei dawei.hu@manchester.ac.uk 0000-0002-2817-8180 Voliotis Aristeidis aristeidis.voliotis@manchester.ac.uk 0000-0001-9710-9851 Bryant Daniel J. daniel.bryant@york.ac.uk 0000-0001-6605-6136 Shaw Marvin D. marvin.shaw@york.ac.uk 0000-0001-9954-243X Hopkins James R. jim.hopkins@york.ac.uk 0000-0002-0447-2633 Hamilton Jacqueline F. jacqui.hamilton@york.ac.uk 0000-0003-0975-4311 Pope Francis D. f.pope@bham.ac.uk 0000-0001-6583-8347 Mudway Ian i.mudway@imperial.ac.uk 0000-0003-1239-5014 Smith Jaclyn jacky.smith@manchester.ac.uk 0000-0001-8837-4928 McFiggans Gordon g.mcfiggans@manchester.ac.uk 0000-0002-3423-7896 University of Manchester Manchester University NHS Foundation Trust Imperial College London University of York Research data supporting the publication "Neurological and Respiratory Outcomes of the HIPTox Controlled Double-Blind Air Pollution Exposure Trial": processed and raw data 10col_life This research data supports the publication "Neurological and Respiratory Outcomes of the HIPTox Controlled Double-Blind Air Pollution Exposure Trial", published in npj clean air, April 2026. The dataset contains demographic information, raw health data, raw cognitive data, processed cognitive data, and estimated marginal means and SDs following analysis. Also included are hourly average concentrations of Particulate Matter and Nitrogen Oxides during air pollution (or clean air) exposure sessions. 2026-04 published npj clean air 10.25500/edata.bham.00001467 Dataset research-data@contacts.bham.ac.uk Geography, Earth & Environmental Sciences nerc NE/W002213/1 yes yes na TRUE Research Fellow Faherty Thomas t.b.s.faherty@bham.ac.uk Single-centre, double-blind clinical trial, 15 healthy volunteers, ≥50 years old with a family history of dementia, undertook four 60-minute controlled exposures to PM-containing pollution mixtures: woodsmoke, diesel exhaust, cooking emissions, and limonene secondary organic aerosol (SOA), and clean air as a control. Each exposure was separated by ≥2-weeks as a washout, and medical oversight was available throughout. Pre- and post-exposure assessments measured respiratory function via spirometry and evaluated cognitive functions including processing speed, executive function, working memory, socio-emotional cognition, and motor control. Manchester, United Kingdom en 2023-05-16 2023-11-21 2023-05 2023-11