Research data supporting the publication "Characterising the Protein-Protein Interaction Between MDM2 and 14-3-3σ; Proof of Concept for Small Molecule Stabilisation"

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data archive 103 disk0/00/00/09/54 2023-07-11 09:56:32 2023-11-24 16:41:25 2023-11-24 15:53:29 data_collection show Kay Danielle F. dxk109@student.bham.ac.uk 0000-0001-9559-7388 Leney Aneika C. a.leney@bham.ac.uk 0000-0002-2066-4950 University of Leicester Research data supporting the publication "Characterising the Protein-Protein Interaction Between MDM2 and 14-3-3σ; Proof of Concept for Small Molecule Stabilisation" 10col_life Native mass spectrometry, protein-protein interactions, molecular stabilisers, tandem mass spectrometry Mass spectrometry raw data to accompany manuscript entitled "Characterising the Protein-Protein Interaction Between MDM2 and 14-3-3σ; Proof of Concept for Small Molecule Stabilisation" by Ward et al. 2024. 2023-11-23 published University of Birmingham https://doi.org/10.25500/edata.bham.00000954 Dataset research-data@contacts.bham.ac.uk School of Biosciences bbsrc epsrc EP/W015803/1 BB/S019456/1 BB/M01116X/1 yes yes yes TRUE Associate Professor Leney Aneika a.leney@bham.ac.uk The data included is in the format of raw files directly taken from the Orbitrap Eclipse mass spectrometer. The data was collected to supplement the manuscript entitled "Characterising the Protein-Protein Interaction Between MDM2 and 14-3-3σ; Proof of Concept for Small Molecule Stabilisation". The methods of how the data was collected are detailed within the manuscript and its corresponding supporting information. The native mass spectrometry data was acquired on an Orbitrap Eclipse mass spectrometer using a nanoelectrospray ionisation source. en 2023-04-01 2023-11-23