Research data supporting the publication "Dissecting the functional behaviour of the differentially phosphorylated prolyl isomerase, Pin1"

Kay, Danielle F. and Ozleyen, Adem and Matas De Las Heras, Christina and Doveston, Richard G. and Leney, Aneika C. (2024) Research data supporting the publication "Dissecting the functional behaviour of the differentially phosphorylated prolyl isomerase, Pin1".

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Dataset Details

Data creator(s):	Creators Email ORCID Kay, Danielle F. dxk109@student.bham.ac.uk orcid.org/0000-0001-9559-7388 Ozleyen, Adem ao278@leicester.ac.uk orcid.org/0000-0003-0195-3383 Matas De Las Heras, Christina cmdlh2@leicester.ac.uk orcid.org/0009-0000-7205-986X Doveston, Richard G. r.g.doveston@leicester.ac.uk orcid.org/0000-0002-7399-9607 Leney, Aneika C. a.leney@bham.ac.uk orcid.org/0000-0002-2066-4950
Research Data Type:	Dataset
DOI:	https://doi.org/10.25500/edata.bham.00001101
Publisher:	University of Birmingham
Funder:	Biotechnology and Biological Sciences Research Council
Keywords:	Native mass spectrometry, proteomics, fluorescence polarisation, isomerisation assays, prolyl isomerase Pin1, phosphorylation
Managing organisational unit:	Colleges (2008 onwards) > College of Life & Environmental Sciences
UoB School, Department or Institute:	School of Biosciences
Date:	30 April 2024

Additional Details

Additional Details

Project/Grant:	BB/M01116X/1, BB/S019456/1
Primary language:	English
Collection period:	From To 2022 2024
Data collection method:	The data was collected to supplement the manuscript entitled "Dissecting the functional behaviour of the differentially phosphorylated prolyl isomerase, Pin1". The methods of how the data was collected are detailed within the manuscript and its corresponding supporting information. The mass spectrometry data was acquired on the Orbitrap HF and Orbitrap Eclipse mass spectrometers using nanoelectrospray ionisation sources. The spectroscopic readings were collected using a CLARIOstar Plus microplate reader.
Data processing and preparation activities:	The mass spectrometry data included is in the format of raw files directly taken from the QExactive HF and Orbitrap Eclipse mass spectrometers. The spectroscopic data is provided within an Excel document.
Depositing User:	Aneika Leney
Date Deposited:	30 Apr 2024 15:09
Last Modified:	30 Apr 2024 15:23

Available Files

Data

Raw data_phosph ... atic Assay.xlsx Raw data_phosph ... atic Assay.xlsx Raw data_phosph ... atic Assay.xlsx Access option: Open File: Raw data_phosphorylation paper_FP_Enzymatic Assay.xlsx Content type: Data Metadata Revision: 8 Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet Licence: File size: 101kB File checksum: 202c977f8bebd14b37cd27f5ae608069

Pin1 phos native.zip Pin1 phos native.zip Pin1 phos native.zip Access option: Open File: Pin1 phos native.zip Content type: Data Metadata Revision: 7 Mime-Type: application/zip Licence: File size: 13MB File checksum: be2db3d723424c23d28bfa7511d5fc49

LC-MS.zip LC-MS.zip LC-MS.zip Access option: Open File: LC-MS.zip Content type: Data Metadata Revision: 6 Mime-Type: application/zip Licence: File size: 3GB File checksum: 24867896774142eb25e5879ff679241d

Pintide binding.zip Pintide binding.zip Pintide binding.zip Access option: Open File: Pintide binding.zip Content type: Data Metadata Revision: 6 Mime-Type: application/zip Licence: File size: 19MB File checksum: e6c5766fe994d700657d47fe3dd067ad

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Readme_data summary.xlsx Readme_data summary.xlsx Readme_data summary.xlsx Access option: Open File: Readme_data summary.xlsx Content type: ["content_typename_readme" not defined] Metadata Revision: 8 Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet Licence: File size: 11kB File checksum: 0bd055847271ec2b7ff4b6870e4064a2

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